Insomnia doubles risk of heart attack, stroke, research shows

















The study by researchers in Taiwan found that people with insomnia were twice as likely to have heart attacks or strokes than those without the sleep disorder during the trial’s four-year period. The research was presented Monday at the American Heart Association meeting in Los Angeles.













The findings add to previous research showing not enough sleep can contribute to high blood pressure, and waking too early may raise heart risks. Sleep should be part of the patient-doctor discussion during checkups, said Kristen Knutson, a sleep researcher who wasn’t part of the study.


“A lot of people and many physicians don’t ask about sleep,” said Knutson, an assistant professor in the Department of Medicine at the University of Chicago. “The first thing is to talk to their patients and also for the patients to talk to their doctors about their sleep and discussing sleep as one of the many important health behaviors like diet and exercise.”


No one is certain how lack of sleep contributes to heart attacks and strokes, she said. It may be that the body’s “fight or flight” system is more active with not enough sleep, which can increase heart rate and over time increase blood pressure and raise the risk for cardiovascular disease, she said.


Chronic insomnia affects about 1 in 5 adults and is also a risk factor for depression, substance abuse and impaired waking function, according to the National Institutes of Health.8f67d  basic Insomnia doubles risk of heart attack, stroke, research shows


Diseases/Conditions News Headlines – Yahoo! News



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Obama's lease renewed despite tough economic times

WASHINGTON (AP) — His lease renewed in trying economic times, President Barack Obama claimed a second term from an incredibly divided electorate and immediately braced for daunting challenges and progress that comes only in fits and starts.

"We have fought our way back and we know in our hearts that for the United States of America, the best is yet to come," Obama said.

The same voters who gave Obama another four years also elected a divided Congress, re-upping the dynamic that has made it so hard for the president to advance his agenda. Democrats retained control of the Senate; Republicans renewed their majority in the House.

It was a sweet victory for Obama, but nothing like the jubilant celebration of four years earlier, when his hope-and-change election as the nation's first black president captivated the world. This time, Obama ground out his win with a stay-the-course pitch that essentially boiled down to a plea for more time to make things right and a hope that Congress will be more accommodating than in the past.

The vanquished Republican, Mitt Romney, tried to set a more conciliatory tone on the way off the stage.

"At a time like this, we can't risk partisan bickering," Romney said after a campaign filled with it. "Our leaders have to reach across the aisle to do the people's work."

House Speaker John Boehner spoke of a dual mandate, saying, "If there is a mandate, it is a mandate for both parties to find common ground and take steps together to help our economy grow and create jobs."

Senate Republican Leader Mitch McConnell had a more harsh assessment.

"The voters have not endorsed the failures or excesses of the president's first term," McConnell said. "They have simply given him more time to finish the job they asked him to do together" with a balanced Congress.

Obama claimed a commanding electoral mandate — at least 303 electoral votes to 206 for Romney — and had a near-sweep of the nine most hotly contested battleground states.

But the close breakdown in the popular vote showed Americans' differences over how best to meet the nation's challenges. With more than 90 percent of precincts reporting, the popular vote went 50 percent for Obama to 48.4 percent for Romney, the businessman-turned-politician who had argued that Obama had failed to turn around the economy and said it was time for a new approach keyed to lower taxes and a less intrusive government.

Obama's re-election assured certainty on some fronts: His signature health-care overhaul will endure, as will the Wall Street reforms enacted after the economic meltdown. The drawdown of troops in Afghanistan will continue apace. And with an aging Supreme Court, the president is likely to have at least one more nomination to the high court.

The challenges immediately ahead for the 44th president are all too familiar: an economy still baby-stepping its way toward full health, 23 million Americans still out of work or in search of better jobs, civil war in Syria, an ominous standoff over Iran's nuclear program, and more.

Sharp differences with Republicans in Congress on taxes, spending, deficit reduction, immigration and more await.

And even before Obama gets to his second inaugural on Jan. 20, he must grapple with the threatened "fiscal cliff" — a combination of automatic tax increases and steep across-the-board spending cuts that are set to take effect in January if Washington doesn't quickly come up with a workaround budget deal. Economists have warned the economy could tip back into recession absent a deal.

Despite long lines at polls in many places, turnout overall looked to be down from four years ago as the president pieced together a winning coalition of women, young people, minorities and lower-income voters that reflected the country's changing demographics. Obama's superior ground organization in the battleground states was key to his success.

The president's victory speech — he'd written a concession, too, just in case — reflected the realities of the rough road ahead.

"By itself the recognition that we have common hopes and dreams won't end all the gridlock, or solve all our problems or substitute for the painstaking work of building consensus and making the difficult compromises needed to move this country forward," Obama said.

"But that common bond is where we must begin. Our economy is recovering. A decade of war is ending. A long campaign is now over, and whether I earned your vote or not, I have listened to you, I have learned from you and you have made me a better president."

The president said he hoped to meet with Romney and discuss how they can work together. They may have battled fiercely, he said, "but it's only because we love this country deeply."

Romney's short concession — with misplaced confidence, he'd only prepared an acceptance speech — was a gracious end note after a grueling campaign.

He wished the president's family well and told subdued supporters in Boston, "I so wish that I had been able to fulfill your hopes to lead the country in a different direction, but the nation chose another leader and so Ann and I join with you to earnestly pray for him and for this great nation."

Obama's re-election was a remarkable achievement given that Americans are anything but enthusiastic about the state they're in: Only about 4 in 10 voters thought the economy is getting better, just one quarter thought they're better off financially than four years ago and a little more than half think the country is on the wrong track, exit polls showed.

But even now, four years after George W. Bush left office, voters were more likely to blame Bush than Obama for the fix they're in.

It wasn't just the president and Congress who were on the ballot. Voters around the country considered ballot measures on a number of divisive social issues, with Maine and Maryland becoming the first states to approve same-sex marriage by popular vote while Washington state and Colorado legalized recreational use of marijuana.

From the beginning, Obama had an easier path than Romney to the 270 electoral votes needed for victory. The most expensive campaign in history was narrowly targeted at people in nine battleground states that held the key to victory, and the two sides drenched voters there with more than a million ads, the overwhelming share of them negative.

Obama claimed at least seven of the battleground states, most notably Ohio, the Ground Zero of campaign 2012. He also got Iowa, New Hampshire, Colorado, Nevada, Virginia and Wisconsin, and he was ahead in Florida. Romney got North Carolina.

Overall, Obama won 25 states and the District of Columbia and was leading in too-close-to-call Florida. Romney won 24 states.

It was a more measured victory than four years ago, when Obama claimed 365 electoral votes to McCain's 173, winning with 53 percent of the popular vote.

Obama was judged by 53 percent of voters to be more in touch with people like them. More good news for him: Six in 10 voters said that taxes should be increased. And nearly half of voters said taxes should be increased on income over $250,000, as Obama has called for.

Obama's list of promises to keep includes many holdovers he was unable to deliver on in his first term: rolling back tax cuts for upper-income people, immigration reform, reducing federal deficits, and more.

A second term is sure to produce turnover in his Cabinet: Treasury Secretary Timothy Geithner has made it clear he wants to leave at the end of Obama's first term but is expected to remain in the post until a successor is confirmed. Secretary of State Hillary Rodham Clinton, Obama's rival for the presidency four years ago, is ready to leave too. Defense Secretary Leon Panetta isn't expected to stay on.

To the end, the presidential race was a nail-biter. About 1 in 10 voters said they'd only settled on their presidential choice within the last few days or even on Election Day, and they were closely divided between Obama and Romney. Nearly 1 percent of voters went for Libertarian Party candidate Gary Johnson, who was on the ballot in 48 states.

In an election offering sharply different views on the role of government, voters ultimately narrowly tilted toward Obama's approach.

"We have seen growth in the economy," said 25-year-old Matt Wieczorek, a registered Republican from Cincinnati who backed the president. "Maybe not as fast as we want it to be, but Obama has made a difference and I don't want to see that growth come to an end."

Notwithstanding his victory, Obama will lead a nation with plenty of people who were ready for a change.

"The last four years have been crap," said 73-year-old Marvin Cleveland, a Romney supporter in Roseville, Minn. "Let's try something else."

___

Follow Nancy Benac on Twitter: http://www.twitter.com/nbenac

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Cautious reformers tipped for new China leadership
















BEIJING (Reuters) – China‘s ruling Communist Party will this month unveil its new top leadership team, expected to again be an all-male cast of politicians whose instincts are to move cautiously on reform.


Sources close to the leadership say 10 main candidates are vying for seven seats on the party’s next Politburo Standing Committee, the peak decision-making body which will steer the world’s second-largest economy for the next five years.













Only two candidates are considered certainties going into the party’s 18th congress, which starts on Thursday: leader-in-waiting Xi Jinping and his designated deputy, Li Keqiang, who are set to be installed as president and premier next March.


Of the remaining eight contenders, only one has the reputation as a political reformer and only one is a woman.


Following are short biographies of the candidates, including their reform credentials and possible portfolio responsibilities.


XI JINPING


REFORM CREDENTIALS: Considered a cautious reformer, having spent time in top positions in Fujian and Zhejiang provinces, both at the forefront of China‘s economic reforms.


Xi Jinping, 59, is China‘s vice president and President Hu Jintao’s anointed successor. He will take over as Communist Party boss at the congress and then as head of state in March.


Xi belongs to the party’s “princeling” generation, the offspring of communist revolutionaries. His father, former vice premier Xi Zhongxun, fought alongside Mao Zedong in the Chinese civil war. Xi watched his father purged and later, during the Cultural Revolution, spent years in the hardscrabble countryside before making his way to university and then to power.


Married to a famous singer, Xi has crafted a low-key and sometimes blunt political style. He has complained that officials’ speeches and writings are clogged with party jargon and has demanded more plain speaking.


Xi went to work in the poor northwest Chinese countryside as a “sent-down youth” during the chaos of the 1966-76 Cultural Revolution, and became a rural commune official. He went on to study chemical engineering at Tsinghua University in Beijing and later gained a doctorate in Marxist theory from Tsinghua.


A native of the poor, inland province of Shaanxi, Xi was promoted to governor of southeastern Fujian province in 1999 and became party boss in neighboring Zhejiang province in 2003.


In 2007, the tall, portly Xi secured the top job in China‘s commercial capital, Shanghai, when his predecessor was caught up in a huge corruption case. Later that year he was promoted to the party’s standing committee.


- – - -


LI KEQIANG


REFORM CREDENTIALS: Seen as another cautious reformer due to his relatively liberal university experiences.


Vice Premier Li Keqiang, 57, is the man tipped to be China‘s next premier, taking over from Wen Jiabao.


His ascent will mark an extraordinary rise for a man who as a youth was sent to toil in the countryside during Mao’s Cultural Revolution.


He was born in Anhui province in 1955, son of a local rural official. Li worked on a commune that was one of the first places to quietly revive private bonuses in farming in the late 1970s. By the time he left Anhui, Li was a Communist Party member and secretary of his production brigade.


He studied law at the elite Peking University, which was among the first Chinese schools to resume teaching law after the Cultural Revolution. He worked to master English and co-translated “The Due Process of Law” by Lord Denning, the famed English jurist.


In 1980, Li, then in the official student union, endorsed controversial campus elections. Party conservatives were aghast, but Li, already a prudent political player, stayed out of the controversial vote.


He climbed the party ranks and in 1983 joined the Communist Youth League’s central secretariat, headed then by Hu Jintao.


Li later served in challenging party chief posts in Liaoning, a frigid northeastern rustbelt province, and rural Henan province. He was named to the powerful nine-member standing committee in 2007.


- – - -


WANG QISHAN


REFORM CREDENTIALS: A financial reformer and problem solver with deep experience tackling tricky economic and political problems.


Wang Qishan, 64, is the most junior of four vice premiers and an ex-mayor of Beijing. But he has a keen grasp of complex economic issues and is the only likely member of the Standing Committee to have been chief executive of a corporation, leading the state-owned China Construction Bank from 1994 to 1997. As such, he may take a leading role in shaping economic policy, including trade and foreign investment.


Wang is an experienced negotiator who has led finance and trade negotiations as well as the Strategic and Economic Dialogue with the United States. He is a favorite of foreign investors and has long been seen as a problem solver, sorting out a debt crisis in Guangdong province where he was vice governor in the late 1990s and replacing the sacked Beijing mayor after a cover-up of the deadly SARS virus in 2003.


Wang is also a princeling, son-in-law of a former vice premier and ex-standing committee member, Yao Yilin. His possible portfolio could be chairman of the National People’s Congress (China’s rubber-stamp parliament), head of parliament’s advisory body, executive vice premier (responsible for economic issues) or the party’s top anti-corruption official.


- – - -


LIU YUNSHAN


REFORM CREDENTIALS: A conservative who has kept domestic media on a tight leash.


Liu Yunshan, 65, may take over the propaganda and ideology portfolio for the Standing Committee.


He has a background in media, once working as a reporter for state-run news agency Xinhua in Inner Mongolia, where he later served in party and propaganda roles before shifting to Beijing.


As minister of the party’s Propaganda Department since 2002, Liu has also sought to control China‘s Internet, which has more than 500 million users. He has been a member of the wider Politburo for two five-year terms ending this year.


Liu has not worked directly for the Communist Youth League, but is aligned to it through his lengthy career in an inland, poor province, long ties to the party’s propaganda system and close relationship with Hu Jintao.


- – - -


LI YUANCHAO


REFORM CREDENTIALS: A reformer who has courted foreign investment and studied in the United States.


Li Yuanchao, 61, oversees the appointment of senior party, government, military and state-owned enterprise officials as head of the party’s powerful organization department. On the Standing Committee, he could head the fight against corruption.


Li, whose father was a vice-mayor of Shanghai, has risen far since his parents were persecuted and he was a humble farm hand during the Cultural Revolution.


Politically astute, Li can navigate between interest groups, from Hu’s Youth League power base to the princelings.


As party chief in his native province, Jiangsu, from 2002 to 2007, Li oversaw a rapid rise in personal incomes and economic development, attracting foreign investment from global industrial leaders such as Ford, Samsung and Caterpillar.


He earned mathematics and economics degrees from two of China‘s best universities and a doctorate in law. He also spent time at Harvard University’s Kennedy School of Government in the United States.


- – - -


ZHANG DEJIANG


REFORM CREDENTIALS: A conservative trained in North Korea.


Zhang Dejiang, 65, saw his chances of promotion boosted this year when he was chosen to replace disgraced politician Bo Xilai as Chongqing party boss. He also serves as vice premier in charge of industry, though his record has been tarnished by the downfall of the railway minister last year for corruption.


Zhang is close to former president Jiang Zemin who still wields some influence. He studied economics at Kim Il-sung University in North Korea and is a native of northeast China.


On his watch as party chief of Guangdong, the southern province maintained its position as a powerhouse of China‘s economic growth, even as it struggled with energy shortages, corruption-fuelled unrest and the 2003 SARS epidemic.


- – - – -


ZHANG GAOLI


REFORM CREDENTIALS: A financial reformer with experience in more developed parts of China.


Zhang Gaoli, 65, party chief of the northern port city of Tianjin and a Politburo member since 2007, is seen as a Jiang Zemin ally but also acceptable to President Hu, who has visited Tianjin three times since 2008. Zhang is an advocate of greater foreign investment and he introduced financial reforms in a bid to turn the city into a financial center in northern China.


He was sent to clean up Tianjin, which was hit by a string of corruption scandals implicating his predecessor and the former top adviser to the city’s lawmaking body. The adviser committed suicide shortly after Zhang’s arrival.


A native of southeastern Fujian province, Zhang trained as an economist. He also served as party chief and governor of eastern Shandong province and as Guangdong vice governor.


Zhang is low-key with a down-to-earth work style, and not much is known about his specific interests and aspirations. But with his leadership experience in more economically advanced cities and provinces, including party secretary of the showcase manufacturing and export-driven city of Shenzhen, he could be named executive vice premier.


- – - – -


WANG YANG


REFORM CREDENTIALS: Seen by many in the West as a beacon of political reform.


Wang Yang, 57, is party chief of the export dependent economic hub of Guangdong province. He was not included in a list of preferred Standing Committee candidates drawn up by Xi, Hu and Hu’s predecessor, Jiang Zemin, according to sources close to the leadership, but is firmly in the running.


Born into a poor rural family in eastern Anhui province, Wang dropped out of high school and went to work in a food factory at age 17 to help support his family after his father died. These experiences may have shaped his desire for more socially inclusive policies, including his “Happy Guangdong” model of development designed to improve quality of life.


Concerned about the social impact of three decades of blistering development, he lobbied for social and political reform. However, this approach has drawn criticism from party conservatives and Wang has more recently adopted the party’s more familiar method of control and punishment to keep order.


- – - – -


YU ZHENGSHENG


REFORM CREDENTIALS: Relatively low-key but considered a cautious reformer.


Yu Zhengsheng, 67, is party boss in China‘s financial hub and most cosmopolitan city, Shanghai.


His impeccable Communist pedigree made him a rising star in the mid-1980s until his brother, an intelligence official, defected to the United States. His close ties with Deng Pufang, the eldest son of late paramount leader Deng Xiaoping, spared him the full political repercussions but he was taken off the fast track.


Yu bided his time in ministerial ranks until bouncing back, joining the Politburo in 2002. However, the princeling’s age would require him to retire in 2017 after one term.


- – - – -


LIU YANDONG


REFORM CREDENTIALS: Uncertain.


Liu Yandong, who turns 67 this month, is the only woman given a serious chance to join the Standing Committee but is considered a dark horse. She is a princeling also tied to President Hu’s Youth League faction.


If promoted, she could head up parliament’s advisory body, but her age would also force her to retire after only one term.


Her bigger challenge is that no woman has made it into the Standing Committee since 1949. Not even Jiang Qing, the widow of late Chairman Mao Zedong, made it that far.


Liu, daughter of a former vice-minister of agriculture, is currently the only woman in the 25-member Politburo, a minority in China‘s male-dominated political culture. She has been on the wider Politburo since 2007 as one of five state councilors, a rank senior to a cabinet minister but junior to a vice-premier.


(Reporting by Terril Yue Jones, Ben Blanchard, Benjamin Kang Lim and Sui-Lee Wee in Beijing. Additional reporting by Chris Ip, Grace Li, Jean Lin, Young Wang, Alice Woodhouse and Julie Zhu; Editing by Raju Gopalakrishnan and Mark Bendeich)


World News Headlines – Yahoo! News



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Apple sells three million iPads over first weekend

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Read More..

American composer Elliott Carter dies at age 103
















(Reuters) – Classical composer Elliott Carter, who twice won Pulitzer Prizes in a career that spanned more than 75 years, died on Monday in New York at age 103, music publisher Boosey & Hawkes said.


Carter was awarded Pulitzer Prizes in 1960 and 1973 for string quartet compositions. He composed 158 works, including several at over 100 years of age. One composition for chamber orchestra is scheduled for a world premier in February.













“The great range and diversity of his music has, and will continue to have, influence on countless composers and performers worldwide,” the publisher said. “He will be missed by us all but remembered for his brilliance, his wit and his great canon of work.”


He was inducted into the American Classical Music Hall of Fame in 1998 and celebrated his 100th birthday at New York‘s Carnegie Hall in 2008 with a new work performed by the Boston Symphony Orchestra.


Carter was presented the National Medal of Arts, the highest award given to artists by the United States, in 1985. He also received national honors from Germany and France.


(Reporting by David Bailey; Editing by Cynthia Johnston and Mohammad Zargham)


Music News Headlines – Yahoo! News



Read More..

St Jude device lowers blood pressure in small study
















(Reuters) – St Jude Medical Inc said on Monday its procedure that deadens nerves near the kidneys helped lower blood pressure in a small study of patients whose hypertension could not be controlled with drugs.


Patients in the study who were treated with the Enlightn renal denervation system saw an average reduction of 28 points in systolic blood pressure, which is the first number expressed in a reading, after 30 days. At six months, the 46 patients who received the treatment maintained an average systolic blood pressure reduction of 26 mmHg points.













The results were presented at the annual meeting of the American Heart Association in Los Angeles.


Patients enrolled in the study had an average blood pressure of 176/96 mmHg despite being treated with multiple medications to manage the condition. No serious side effects were reported, St Jude said.


Normal blood pressure is below 120/80 mmHg. Hypertension, or high blood pressure, is a reading above 140/90 mmHg.


Renal denervation is a procedure in which a thin, flexible catheter is threaded through the body to the renal sympathetic nerves near the kidneys. Radiofrequency energy is delivered to disrupt the nerve activity, relieving high blood pressure.


Millions of people have hypertension that is resistant to drugs, putting them at risk of heart attacks and stroke.


The new therapy is not yet approved in the United States, but several products are already available in Europe.


Device makers that have already received approval to sell hypertension devices in Europe include Medtronic, the front-runner, St Jude, Covidien, ReCor Medical and Vessix Vascular.


St Jude shares were up 29 cents, or less than 1 percent, at $ 38.80 in afternoon trading on the New York Stock Exchange.


(Reporting By Susan Kelly and Debra Sherman in Chicago; Editing by Gerald E. McCormick, Leslie Adler and Jim Marshall)


Medications/Drugs News Headlines – Yahoo! News



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Bomb shakes Damascus, opposition holds unity talks
















AMMAN (Reuters) – A bomb exploded near army and security compounds in Damascus, Syrian television reported, and fractured opposition groups seeking to topple President Bashar al-Assad began unity talks abroad to win international respect and arms supplies.


The 50-kilogram (110-pound) bomb, near a large hotel in a heavily guarded district, was described by state media as an attack by “terrorists” – the government’s term for insurgents in the 19-month-old uprising against Assad.













Opposition activists said Sunday’s blast appeared to be the work of the Ahfad al-Rasoul (Grandsons of the Prophet) Brigade, an Islamist militant unit that attacked military and intelligence targets several times in the last two months.


The mainly Sunni rebels have carried out a series of bombings targeting government and military buildings in Damascus this year, extending the war into the seat of Assad’s power.


The Syrian conflict has aggravated divisions in the Islamic world, with Shi’ite Iran supporting Assad — whose Alawite faith derives from Shi’ite Islam — and U.S.-allied Sunni nations such as Saudi Arabia, Turkey and Qatar backing his foes.


The Syrian Network for Human Rights, an activist monitoring group, said government forces had killed 179 people on Sunday. It said most of the dead were civilians killed in shelling of Damascus suburbs and included 14 women and 20 children. The rest were rebels killed in battles in the capital and the northern provinces of Idlib and Aleppo.


Opposition campaigners said the Syrian army shelled rebel positions inside a Palestinian refugee camp on the edge of Damascus on Sunday, killing at least 20 people. They said the Yarmouk camp had become the latest battleground in the war.


In northern Idlib, opposition sources said rebels were forced to halt an offensive to take a big air base because of a shortage of ammunition, a problem that has dogged their campaign to cement a hold on the north by eliminating Assad’s devastating edge in firepower.


Islamist insurgents had launched the attack on the Taftanaz military airport at dawn on Saturday, using rocket launchers and at least three tanks captured from the military.


The Syrian government restricts journalists’ access in Syria, making it difficult to verify reports from the ground.


The Jaafar bin Tayyar Division, a rebel unit in Deir al-Zor, said its fighters had taken control of the al-Ward oilfield near the Iraqi border on Sunday, after overrunning a loyalist outpost that had 40 militiamen defending it.


Rebel commanders, former Syrian officials and the Syrian head of an oil services company familiar with oil production in the area said the fields, mostly not operational, had been under de facto rebel control for months.


FEARS OF WIDER CONFLAGRATION


The conflict began with peaceful protest rallies that morphed into armed revolt when Assad, whose family has ruled Syria since 1971, tried to stamp them out with military might. About 32,000 people have been killed, wide swathes of the major Arab state have been wrecked and the civil war threatens to widen into a regional sectarian conflagration.


The opposition talks that began in Qatar marked the first concerted attempt to meld feuding, disparate groups based abroad and coordinate strategy with rebels fighting in Syria.


Divisions between Islamists and secularists as well as between those inside Syria and opposition figures based abroad have foiled prior attempts to forge a united opposition and deterred Western powers from intervening militarily.


Analysts were skeptical the planned four days of opposition talks in the Qatari capital Doha would bring immediate results.


They aim to broaden the Syrian National Council (SNC), the largest of the overseas-based opposition groups, from some 300 members to 400, to pave the way for talks in Doha on Thursday including other anti-Assad factions to crystallise a coalition.


“The main aim is to expand the council to include more of the social and political components. There will be new forces in the SNC,” Abdulbaset Sieda, current leader of the Syrian National Council, told reporters in Doha ahead of the meeting.


The meetings would also elect a new executive committee and leader for the SNC, he said.


A Qatar-based security analyst, who asked not to be named, said the meetings would bring a small step forward, at most. “The Syrian National Council is just too divided,” he said.


In Cairo, the international mediator on Syria, Lakhdar Brahimi, called on Sunday for world powers to issue a U.N. Security Council resolution based on a deal they reached in June to set up a transitional Syrian government.


But Russian Foreign Minister Sergei Lavrov, speaking at the same news conference, dismissed the need for a resolution and said others were stoking violence by backing rebels. His comments highlighted the impasse over Syria’s civil war.


Russia and China, both permanent council members, have vetoed three Western-backed U.N. draft resolutions condemning Assad’s government for the violence. The other three permanent members are the United States, Britain and France.


(Additional reporting by Rania el Gamal and Regan Doherty in Qatar, Suleiman al-Khalidi in Amman; Editing by Philippa Fletcher and Stephen Powell)


World News Headlines – Yahoo! News



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Apple says sold three million iPads since Friday

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Read More..

Sharon Osbourne has double mastectomy
















LONDON (AP) — Sharon Osbourne says she had a double mastectomy after learning she carries a gene that increases the risk of developing breast cancer.


Osbourne told Hello! magazine that “I didn’t want to live the rest of my life with that shadow hanging over me.”













The 60-year-old “America’s Got Talent” judge, who had colon cancer a decade ago, said that without the surgery, “the odds are not in my favor.”


She added: “It’s not ‘pity me,’ it’s a decision I made that’s got rid of this weight that I was carrying around.”


The magazine went on sale Monday.


Osbourne, husband Ozzy and children Jack and Kelly became rock’s most famous clan thanks to reality show “The Osbournes” a decade ago.


Jack Osbourne, 26, was recently diagnosed with multiple sclerosis.


Entertainment News Headlines – Yahoo! News



Read More..

BioMarin genetic disorder drug meets main goal, shares jump
















(Reuters) – BioMarin Pharmaceutical Inc said a late-stage trial of its experimental genetic disorder drug met the main goal of improving patients’ walking ability when administered weekly, sending the company‘s shares up 25 percent in premarket trading.


The drug, called GALNS, however, did not show any improvement over a placebo when administered every other week.













The trial, named MOR-004, showed that weekly doses of the drug at 2 mg/kg improved the six-minute walk distance of patients by 22.5 meters over the placebo.


However, patients getting the same dose every other week did not show any meaningful or statistically significant change compared to the placebo.


The disorder – Mucopolysaccharidosis Type IVA (MPS IVA), or Morquio A Syndrome – is a rare, inherited disorder caused by the deficiency of a particular enzyme, leading to skeletal dysplasia, short stature and joint abnormalities.


The drug was also tested in another extension trial that showed its benefits continued to improve with further dosage, BioMarin said in a statement.


GALNS was generally well-tolerated and adverse events were similar to those seen in the trials of other enzyme replacement therapies. There were no deaths and no patients withdrew from the study due to adverse events.


BioMarin now plans to submit marketing applications for the drug, starting from the first quarter of 2013.


The company currently has four drugs in the market, two of which are for treating other metabolic disorders caused by the absence of certain enzymes.


Shares of the company closed at $ 37.41 on the Nasdaq on Friday, and were trading at $ 47 before markets opened on Monday. (Reporting by Esha Dey in Bangalore; Editing by Joyjeet Das)


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